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Search Results for " vitamin d3 "

37

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T35501	5,6-trans-Vitamin D3 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A	Vitamin	Metabolism
	5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol）是维生素 D3 的异构体，经光照后在皮肤表面由 Vitamin D3 转化而来。
T6430L	Calcifediol monohydrate 骨化二醇一水合物,25-hydroxy Vitamin D3 monohydrate	Endogenous Metabolite	Metabolism
	Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate) 是维生素 D3 在肝中经羟基化后得到的前激素，是有效的 VDR 抑制剂。
T72726	3-epi-Vitamin D3 Epicholecalciferol
	3-epi-Vitamin D3 (Epicholecalciferol) 是维生素 D3 类似物，是一种Hedgehogpathway 抑制剂，在U87MG 细胞中测定的IC50为 39.2 μM。
T35500	3-epi-25-hydroxy Vitamin D3 3-epi-25-hydroxy Vitamin D3
	3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats. 1.Djekic-Ivankovic, M., Lavery, P., Agellon, S., et al.The C-3α epimer of 25-hydroxycholecalciferol from endogenous and exogenous sources supports normal growth and bone mineral density in weanling ratsJ. Nutr.147(2)141-151(2017)
T6374	Alfacalcidol Bondiol,Etalpha,阿法骨化醇,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol	Others	Others
	Alfacalcidol (Etalpha) 是一种维生素 D3 衍生物，是非选择性的维生素 D 受体活化剂，有用于骨质疏松研究的潜力。
T36919	1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3
	1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].
T13291	VD3-D6 Vitamin D3-26,26,26,27,27,27-d6	Others	Others
	VD3-D6 is the deuterated form of Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.
T29867	ALK-001 C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A
	ALK-001 is a vitamin A analog, which may be used to treat Stargardt disease.
T13610	Chol-5-en-24-al-3β-ol Vitamin D3 derivative	Others	Others
	Chol-5-en-24-al-3β-ol is a steroid compound.
T19123	3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether	Others	Others
	3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 is a Vitamin D3 derivative.
T24166	Inecalcitol TX 522,TX-522,TX522,伊奈骨化醇	Apoptosis	Apoptosis
	Inecalcitol (TX 522) 是一种独特的维生素 D3 类似物，可诱导细胞凋亡，有抗癌活性。它是一种具有口服活性维生素 D 受体激动剂，Kd 为 0.53 nM。
T13911	Tacalcitol monohydrate Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate	Cysteine Protease	Proteases/Proteasome
	Tacalcitol monohydrate(Curatoderm monohydrate) 是一种维生素 D3 类似物，能通过调节钙离子促进骨发育，可用于研究银屑病。
TQ0244	Calcipotriol monohydrate 钙泊三醇一水合物,卡泊三醇一水合物
	Calcipotriol monohydrate 是维生素 D3 的类似物，对维生素 D 受体具有高亲和力。Calcipotriol monohydrate 可用于银屑病研究。
T16015	Maxacalcitol 马沙骨化醇,22-Oxacalcitriol	Others	Others
	Maxacalcitol (22-Oxacalcitriol) 是非血钙维生素 D3的一种类似物，是 VDR 样受体的配体。
T16023L	(24R)-MC 976	Others	Others
	(24R)-MC 976 is a derivative of Vitamin D3.
T38553	Previtamin D3 Previtamin D3
	Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).
T16023	MC 976	Ras	GPCR/G Protein; MAPK
	MC 976 is a derivative of Vitamin D3.
T16023L2	(24S)-MC 976	Others	Others
	(24S)-MC 976 is a derivative of Vitamin D3.
T35524	(1S)-Calcitriol
	(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1]. 3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1]. [1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydr...
T17031	TEI-9647	Others	Others
	TEI-9647 is a 1α,25-dihydroxy vitamin D3-26,23-lactone (1α,25-lactone) analog and is an effective VDR/vitamin D-responsive element (DRE)-mediated genomic actions antagonist.
T19227	Calcitriol Impurities A	Others	Others
	Calcitriol Impurities A refers to the contaminants found in Calcitriol, the hormonally active metabolite of vitamin D3, which serves to activate the vitamin D receptor.
T19610	(24S)-24,25-Dihydroxyvitamin D3 (24S)-24,25-Dihydroxycholecalciferol	Others	Others
	(24S)-24,25-Dihydroxyvitamin D3 undergoes various levels of hydroxylation to form active vitamin D3 analogs.
T13290	VD2-D3	Others	Others
	VD2-D3 is a deuterated form of vitamin D.
T40601	Lumisterol 3 (>90%) CholecalciferolEPImpurityA,Lumisterol 3 (>90%),9β,10α-Cholesta-5,7-dien-3β-ol
	Lumisterol 3 (>90%; 9β,10α-Cholesta-5,7-dien-3β-ol) is a predominant secosteroid metabolite found in humans, belonging to the class of vitamin D3 photoisomer derivatives. It is utilized in the synthesis of vitamin D.
T19226	Calcitriol Derivatives	Others	Others
	Calcitriol Derivatives is an analog of vitamin D3.
T10663	Calcitriol-d6 Calcitriol D6,骨化三醇 D6	Others	Others
	Calcitriol D6 is the deuterated form of Calcitriol, which is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor.
T37312	Isotachysterol 3
	Isotachysterol 3, an analog of 1,25-dihydroxy Vitamin D3, was found to enhance intestinal calcium transport and stimulate bone calcium mobilization in anephric rats[1].
T11089	Doxercalciferol-D3	Others	Others
	Doxercalciferol-d3 is the deuterated form of Doxercalciferol and ACTS as vitamin D receptor activator (VDRA), which is a vitamin D2 analogue.
T11643	Impurity B of Calcitriol 1β,25-Dihydroxyvitamin-D3,1-Epicalcitriol	Others	Others
	Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
T63626	Pefcalcitol
	Pefcalcitol 是新型的抗银屑病前药候选药物，含有16-en-22-oxa-维生素 D3结构。
T11645	Impurity C of Calcitriol	Others	Others
	Impurity C of Calcitriol是 Calcitriol 的杂质。Impurity C of Calcitriol 可用于合成维生素D3。
T75085	Doxercalciferol-d
	Doxercalciferol-d33是 Doxercalciferol 的氘化形式，是维生素 D2类似物，能作为维生素D 受体活化剂。
T11952	Maxacalcitol-D6	Others	Others
	Maxacalcitol-D6 is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.Maxacalcitol-D6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol).
T36593	TEI-9648
	TEI-9648, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research[1][2]. TEI-9648 (10-1000 nM) dose-dependently blocks the reciprocal changes of CD11b and CD71 expression associated with HL-60 cell differentiation induced by 1α,25(OH)2D3[1]. TEI-9648 has cons...
T75123	Maxacalcitol-d
	Maxacalcitol-d66是Maxacalcitol (22-Oxacalcitriol)的氘化形式，是非血钙维生素D3类似物和VDR 样受体VDR 配体。
T10661	Calcifediol-D6 骨化二醇 D6	Others	Others
	Calcifediol-D6 is the deuterated form of Calcifediol, which is a prehormone that is produced in the liver by hydroxylation of vitamin D3 by the enzyme cholecalciferol 25-hydroxylase.
T19228	Calcitriol Impurities D 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3	Antiviral	Immunology/Inflammation
	Calcitriol Impurities D (24-Homo Calcitriol) 是维生素的一种激素形式，可促进HL-60人早幼粒细胞白血病细胞分化为单核细胞。Calcitriol Impurities D 具有骨吸收活性，抑制人类免疫缺陷病毒在人体细胞中的复制。Calcitriol Impurities D 具有抗病毒活性们可以用于治疗艾滋病和病毒感染。

化合物

5,6-trans-Vitamin D3

Cat.No: T35501

Synonym: 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A

Target: Vitamin

Calcifediol monohydrate

Cat.No: T6430L

Synonym: 骨化二醇一水合物,25-hydroxy Vitamin D3 monohydrate

Target: Endogenous Metabolite

3-epi-Vitamin D3

Cat.No: T72726

Synonym: Epicholecalciferol

3-epi-25-hydroxy Vitamin D3

Cat.No: T35500

Synonym: 3-epi-25-hydroxy Vitamin D3

Cat.No: T6374

Synonym: Bondiol,Etalpha,阿法骨化醇,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol

Target: Others

1α-Hydroxy-3-epi-vitamin D3

Cat.No: T36919

Synonym: 1α-Hydroxy-3-epi-vitamin D3

Cat.No: T13291

Synonym: Vitamin D3-26,26,26,27,27,27-d6

Target: Others

Cat.No: T29867

Synonym: C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A

Chol-5-en-24-al-3β-ol

Cat.No: T13610

Synonym: Vitamin D3 derivative

Target: Others

3-O-(2-Aminoethyl)-25-hydroxyvitamin D3

Cat.No: T19123

Synonym: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether

Target: Others

Cat.No: T24166

Synonym: TX 522,TX-522,TX522,伊奈骨化醇

Target: Apoptosis

Tacalcitol monohydrate

Cat.No: T13911

Synonym: Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate

Target: Cysteine Protease

Calcipotriol monohydrate

Cat.No: TQ0244

Synonym: 钙泊三醇一水合物,卡泊三醇一水合物

Cat.No: T16015

Synonym: 马沙骨化醇,22-Oxacalcitriol

Target: Others

Cat.No: T16023L

Target: Others

Cat.No: T38553

Synonym: Previtamin D3

Cat.No: T16023

Target: Ras

Cat.No: T16023L2

Target: Others

(1S)-Calcitriol

Cat.No: T35524

Cat.No: T17031

Target: Others

Calcitriol Impurities A

Cat.No: T19227

Target: Others

(24S)-24,25-Dihydroxyvitamin D3

Cat.No: T19610

Synonym: (24S)-24,25-Dihydroxycholecalciferol

Target: Others

Cat.No: T13290

Target: Others

Lumisterol 3 (>90%)

Cat.No: T40601

Synonym: CholecalciferolEPImpurityA,Lumisterol 3 (>90%),9β,10α-Cholesta-5,7-dien-3β-ol

Calcitriol Derivatives

Cat.No: T19226

Target: Others

Cat.No: T10663

Synonym: Calcitriol D6,骨化三醇 D6

Target: Others

Isotachysterol 3

Cat.No: T37312

Doxercalciferol-D3

Cat.No: T11089

Target: Others

Impurity B of Calcitriol

Cat.No: T11643

Synonym: 1β,25-Dihydroxyvitamin-D3,1-Epicalcitriol

Target: Others

Cat.No: T63626

Impurity C of Calcitriol

Cat.No: T11645

Target: Others

Doxercalciferol-d

Cat.No: T75085

Maxacalcitol-D6

Cat.No: T11952

Target: Others

Cat.No: T36593

Cat.No: T75123

Cat.No: T10661

Synonym: 骨化二醇 D6

Target: Others

Calcitriol Impurities D

Cat.No: T19228

Synonym: 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3

Target: Antiviral

Cat. No.	Product Name	Target	Signaling Pathways
T1135	Vitamin D3 维生素D3,Cholecalciferol,Colecalciferol	Endogenous Metabolite	Metabolism
	Vitamin D3 (Cholecalciferol) 是维生素 D 的一种天然存在形式，代谢激活后可以诱导细胞分化和癌细胞增殖。
T41072	Vitamin D3 octanoate Vitamin D3 octanoate
	Vitamin D3 octanoate, an ester derived from vitamin D3, is commonly known as cholecalciferol. Cholecalciferol is a naturally occurring form of vitamin D with notable properties such as inducing cell differentiation and impeding cancer cell proliferation.
T6430	Calcifediol 25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇	Endogenous Metabolite	Metabolism
	Calcifediol (U 32070E) 是由维生素 D3 在肝中经羟基化后得到的前激素，是 VDR 的有效抑制剂。
T6316	Calcitriol Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3	Endogenous Metabolite	Metabolism
	Calcitriol (1,25-Dihydroxyvitamin D3) 是一种维他命 D 的代谢物，一种维他命 D 受体 (VDR) 的激动剂 (IC50=0.4 nM)。Calcitriol 增加肠道对钙和磷的吸收，并与甲状旁腺激素一起增加了骨吸收。
TL0007	Bisdemethoxycurcumin 双去甲氧基姜黄素,Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; Stem Cells
	Bisdemethoxycurcumin (Curcumin III) 是一种具有抗炎及抗氧化作用的姜黄素。
T19108	24, 25-Dihydroxy VD3 24,25-二羟基维生素 D3	Others	Others
	24, 25-Dihydroxy VD3 is closely related to 1,25-dihydroxy vitamin D3, the active form of vitamin D3.
T13490	25,26-Dihydroxyvitamin D3 25,26-Dihydroxycholecalciferol	Others	Others
	25,26-Dihydroxyvitamin D3 is a metabolite of vitamin D3 with intestinal calcium transport activity.

天然产物

Cat.No: T1135

Synonym: 维生素D3,Cholecalciferol,Colecalciferol

Target: Endogenous Metabolite

Vitamin D3 octanoate

Cat.No: T41072

Synonym: Vitamin D3 octanoate

Cat.No: T6430

Synonym: 25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇

Target: Endogenous Metabolite

Cat.No: T6316

Synonym: Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3

Target: Endogenous Metabolite

Bisdemethoxycurcumin

Cat.No: TL0007

Synonym: 双去甲氧基姜黄素,Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

24, 25-Dihydroxy VD3

Cat.No: T19108

Synonym: 24,25-二羟基维生素 D3

Target: Others

25,26-Dihydroxyvitamin D3

Cat.No: T13490

Synonym: 25,26-Dihydroxycholecalciferol

Target: Others

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